By using an orderly approach, the clinician is able to correlate
bedside observations and
laboratory findings with
pathophysiology and the basic elements of
cardiac pathology, as shown on the following specimen.
This is a pathology specimen from a patient with a bicuspid aortic valve. The aortic root has been opened at a commissure, and the arrows identify the two cusps. Over many years, such valves may fibrose and become calcified.
Bicuspid aortic valves may be associated with no hemodynamic abnormalities, with aortic regurgitation, aortic stenosis or a combination of both.